Latest news https://c-tnbs.uk-essen.de/index.php <![CDATA[Funding period for SFB 1280 extended: Research on the 2nd memory enters the next round]]> What happens in the brain with acquired knowledge that is no longer really important? Researchers from the medical faculties of the University of Duisburg-Essen (UDE) and the Ruhr-Universität Bochum (RUB) are seeking and finding answers to this exciting question. Since 2017, they have been working on this as part of the Collaborative Research Center "Extinction Learning". Due to the successes already achieved, the German Research Foundation has now approved funding of around 10 million euros for the next 4 years.

The SFB 1280 "Extinction Learning" has set itself ambitious goals for the second funding period: "In our research, we want to comprehensively understand the mechanisms of extinction learning, from genes to the brain to behavior," explains spokesperson Pro...

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<![CDATA[Strengthening translational and interdisciplinary research approaches]]> Joint symposium of the research foci "Immunology and Infectiology" and "Translational Neurosciences and Behavioral Sciences" (TNBS)

Despite the difficult conditions caused by the ongoing SARS CoV-2 pandemic, the joint symposium of the two research foci of the Faculty of Medicine took place virtually on April, 8th 2021. The webinar symposium aimed to establish and further develop the cross-disciplinary expertise of both research foci and the already very well established links between theoretical and clinical working groups.

From the Department of Neurology at Münster University Hospital, Prof. Dr. Heinz Wiendl presented innovative research approaches on chronic inflammatory diseases of the central nervous system in his guest lecture. The other 6 tandem lectures...

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<![CDATA[Foundation of the Center for Translational Neuro- and Behavioral Sciences (C-TNBS)]]> Special recognition for 7 research institutes and 8 clinics of the Essen University Medical Center: Together they will form the "Center for Translational and Behavioral Neuroscience" (C-TNBS) in the future. The C-TNBS will further bundle scientific and clinical activities, bringing medical theory and practice even closer together. The merger was made possible by the Executive Board of the University Hospital Essen (UK Essen) and the Dean's Office of the Medical Faculty of the University of Duisburg-Essen (UDE).

Patients and researchers will benefit from the cooperation between the institutions. Locally, new synergies are created among the researching institutes and treating clinics - disease patterns can thus be investigated faster and better by experts. Series of...

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<![CDATA[Scientific Council: High potential for Translational Neuro- and Behavioral Sciences]]> In its latest report, the Scientific Council has attested a high potential for the research focus Translational Neuro- and Behavioral Sciences at the Medical Faculty of the University of Duisburg-Essen. According to the council, this is due to the excellent networking in this field and to the fact that excellent researchers have been acquired to Essen in the past years. "We were very pleased with the vote of the council and are encouraged to further intensify our efforts to attract large collaborative research projects. With the approval of the DFG research group ImmunoStroke, we have already achieved our first great success this year," says Prof. Christoph Kleinschnitz, Director of the Clinic for Neurology, who heads the research center together with Prof. Manfred...

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<![CDATA[Major Instrumentation granted for Clinic for Neurosurgery]]> The Clinic for Neurosurgery under the direction of Prof. Dr. Ulrich Sure was able to acquire major instrumentation for intraoperative imaging as part of a state major instrumentation grant of the Deutsche Forschungsgemeinschaft. Under this programme, major instrumentation is procured for German universities and university clinics and financed by the states/universities. The DFG is commissioned by the states to review proposals for major instruments that are to be used for research, teaching and training, or for medical care. The funds can serve this purpose either directly or indirectly. The robot-supported X-ray device is particularly well suited for patients who, for example, expect difficult operating conditions due to comorbidity. In this way, patients with...

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<![CDATA[Learned immunosuppression might be supportive in treatment of chronic inflammatory autoimmune diseases]]> A recent study published in Arthritis & Rheumatology showed that inflammatory symptoms in a experimentally induced arthritis in rats are attenuated by using learned immunosuppressive placebo responses.

Therapy of chronic inflammatory autoimmune diseases such as rheumatoid arthritis requires long lasting if not continuous treatment with immunosuppressive drugs. However, therapy with most small-molecule immunosuppressive drugs commonly induces unwanted toxic side effects. In search for strategies to overcome this disadvantage, it has been suggested to use learned immunopharmacological placebo responses for drug dose reduction during therapy, while simultaneously maintaining treatment efficacy. Such approaches are based on classical conditioning of physiological...

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<![CDATA[Neurophysiological Seminar Winter Semester 2019]]> The Department of Neurology, under the organization of Prof. Dr. Dagmar Timmann-Braun, invites to the next series of the neurophysiological seminar. In the sense of the translational approach, top-class speakers and interesting lectures are expected. 2 CME training points have been applied for by the organizers. All events will take place on Thursday from 17.15 - 18.45h in conference room 2, second floor, Medizinisches Zentrum.

 
 
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<![CDATA[Masao Ito Award for Best Poster for Lana Inoue]]> Lana Inoue has received the Masao Ito Award for Best Poster for the presentation of her poster "Can cerebellar-dependent motor responses modulate extinction of conditioned fear? (Inoue L, Batsikadze G, Ernst TM, Merz CJ, Timmann D)" at the 10th International Annual Meeting of the Society for Research on the Cerebellum and Ataxias (SRCA) on 16-17 May 2019 in Sheffield, UK. Ms. Inoue was able to assert herself as a young medical doctoral student in a field with top-class staff. Ms. Inoue is a fellow of the ELAN doctoral college (Essen training programme "Laboratory and Science" for junior doctors), which is sponsored by the Else Kröner Fresenius Foundation. She is preparing her doctoral thesis in Professor Timmann's group at the Clinic for Neurology. The project is...

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<![CDATA[Review: 2. TNBS Symposium]]> At its second symposium on 16 May 2019, the research focus Translational Neuro- and Behavioural Sciences of the University Hospital Essen was once again broadly positioned: Participating institutes and clinics presented their overarching research topics from the fields of neuroanatomy, neuropathology, neurology, endocrinology and psychiatry. As guest speaker, Prof. Chadi Touma from the University of Osnabrück supplemented the scientific program with his lecture on translational research on the behavioral endocrinology of affective disorders. The successful concept will be continued in a planned third symposium, the speakers Univ.-Prof. Christoph Kleinschnitz and Univ.-Prof. Manfred Schedlowski already announced.

Impressions

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<![CDATA[TNBS Kick-Off Symposium]]> It is our great pleasure to invite you to the kick-off symposium of the new center for Translational Neuro- and Behavioral Sciences of the faculty of medicine of the University of Duisburg-Essen. For many years, the neuroscience and behavioral sciences have been a clinical and academic asset in Essen. Examples include an exceptionally strong and high-class publication output, participation in collaborative research, such as the DFG Collaborative Research Centers 1280 (Extinction Learning) and 240 (Platelets), the DFG Research Groups 1328 (Placebo / Nocebo) and 1581 (Learning / Extinction), the DFG Research Training Group 2098 (sphingomyelinases) as well as on European projects (eg Horizon 2020 program). No fewer than 17 clinics and institutes as well as 25...

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